Like informal settlements in cities across Africa, Mukuru is vulnerable to climate hazards like extreme rainfall, floods, water- and vector-borne diseases, extreme heat, fires, and water scarcity. This is due to its precarious location, poor infrastructure, and high levels of poverty. Residents also have little say in decision-making processes. As a result, Mukuru lacks infrastructure and resources to deal with climate-related risks. Across Africa, climate resilience in informal settlements requires urgent attention. Locally-led planning efforts under the SPA have addressed existing gaps in service provision. These investments have reduced residents’ climate vulnerability. The SPA serves as an important model for upgrading at scale to build climate resilience in informal settlements.